For the busiest of us, idle games have a special appeal, and the cute Pew Pew Slime Idle RPG is there to charm you with its lovely art style. You start as a measly slime blob, but you will soon be faced with the choice of picking an affinity for your slime protagonist. While these choices will ultimately lead you to very strong advanced mutations, depending on your playstyle, it's best to choose early how you want to spec your blob so you can go above and beyond with the most powerful mutated slime. Take a look at our Pew Pew Slime Idle Mutation Tier List to find out how to guide the evolution of your slime!
Pew Pew Slime Idle RPG Best Mutation Tier List
In our best mutation tier list, we're primarily be going to look at the bare performance of the character slime mutation itself. While all slimes carry a setup of skills and a team of pals, this is introducing additional RNG factors that draw away the focus from what you can choose: the slime mutation itself. This is how we ranked best mutations in Pew Pew Slime Idle RPG:
- S Tier Mutations: Best standalone mutations, that are less dependent on gacha elements.
- A Tier Mutations: Great mutations if you plan to invest more time and resources into the game.
- B Tier Mutations: Mutations that lack in performance without significant investment.

S Tier Pew Pew Slime Idle RPG Mutations
| Slime Mutation | Pros & Cons |
|---|---|
![]() Frost Seraph Attribute type Projectile Mimicry | ATK SPD Basic Attack Crit EVA Attribute DMG Extra bullets Attribute Domain + Frost Seraph, and its ultimate form Frost Sovereign is the first mutation derived from Projectile Mimicry. It's a special basic attack type mutation that focuses on specific element attribute basic attacks and their amplifications. Its early passive skill is focused on adding frost attribute damage. + The other skills throw frost bombs that freeze mobs every two basic attacks via the Frost Realm, giving it some degree of crowd control which serves as a defensive strategy too. Frost realm further inflicts attribute damage as DoT. This is especially important because Frost Seraph doesn't have any defensive buffs in its kit. + The freezing combo gives this mutation a slower, but reliable and consistent damaging setup which is only further enhanced by whichever skills and pals you throw into the field with them, so it's possible to fine tune its performance to your ability and liking. |
A Tier Pew Pew Slime Idle RPG Mutations
| Slime Mutation | Pros & Cons |
|---|---|
![]() Earth Spirit Basic Attack Type Projectile Mimicry | ATK SPD Basic ATK DMG Basic Attack Crit EVA Extra bullets Double Trigger + The other Projectile Mimicry mutation Earth Spirit and its ultimate Gaia Spirit early passive skill focuses on directly enhancing the basic attack damage for extra numbers on the field. + Its other skills fire Chlorophyll Homing Bullets that scale of Basic Attack damage every two basic attacks, later further enhanced with even more bullets fired on every basic attack. All the attacks pile up into the biggest flat numbers a Mutation can dish out without the support of high rarity skills and pals. − It stays behind its frost sibling for the lack of Attribute damage that can save it in life threatening situations, as it also lacks any sort of defensive trait. |
Abyssal TidelordSkill Type Skill Mutation | Skill Crit Skill ATK DMG DMG RED Skill recharge SPD Extra Skill Double Trigger + The Abyssal Tidelord and its ultimate shape Undersea Siren focus on dishing damage through enhanced skills. Its early passive speeds up the recovery of all skills, which guarantees superb damage output through faster procs. + Later passives grant the Tidelord a damaging tentacle summon around it which kicks into play whenever a skill is being cast. It functions as both a great offensive and defensive trait. Finally, the last passive also adds more tentacles and an additional skill charge speed which allow skills to turn this mutation into a real beast. − The only real setback of this mutation is that most of the damage is coming from skills, and these have to be rolled for time and time again. |
![]() Nocturnis Dragonlord Skill Type Skill Mutation | Skill Crit Skill ATK DMG Skill Crit DMG DMG RED Timed DMG Boost Timed Skill + Instead of speed, the Skill Mutation Nocturnis Dragonlord and its ultimate form Fallen Dragon enhances the skills' crit DMG, meaning this is a slower variant of the Skill type. + Later passives include a huge boost to its Skill ATK DMG and a Dragonbone Swamp field summon which deals massive damage in the area every 10 seconds. − While its damage is very potent, the Dragonlord needs 10 seconds from the start of every battle to wind up the Skill ATK DMG boost, a time which leaves him open to take stacking damage, thus lowering his overall capacity. |
B Tier Pew Pew Slime Idle RPG Mutations
| Slime Mutation | Pros & Cons |
|---|---|
![]() Behemoth Guardian Pal Type Pal Symbiosis | Pal ATK DMG Pal ATK SPD Pal Crit DMG DEF DMG RED BOSS DMG Low HP recovery Additional Pal + Instead of dealing the bulk of damage through skills or basics, Behemoth Guardian and its ultimate form Beast Hero rely on their pal team to deal the damage through multiple boosts they give them. + This mutation's basic passive skill adds a special boss damage multiplier and an overall damage reduction buff to its team. Later skills focus on emergency health regen which kicks in when the Guardian is at half of its health, and more importantly summon a special additional crit-boosted pal Slime Behemoth. − Pals sometimes move unpredictably around the field, especially if you're running around manually to dodge special boss moves. This puts the predictability of the whole Pal Symbiosis tree at a lower degree. |
![]() Punk Squad Pal Type Pal Symbiosis | Pal ATK DMG Pal ATK SPD Pal Crit DEF Timed bonus damage Extra Bullets + Punk Squad and its ultimate form Thunderbolt Squad focus everything on their pals, and all three passives are directly boosting pals' crit rate and damage, with the last one giving pals an extra Can Bomb skill. − Like with Behemoth Guardian, this mutation also suffers from the way pals behave when you're moving erratically around the field to escape fatal boss damage. This mutation has no defensive protections for itself, which in turn gives less opportunity to the pals to deal damage. |
Whether you choose a more independent mutation, or you decide that you want to roll add-ons for the ones whose kits you simply like better, you'll have access to skills and pals no matter what. Let's take a look at which skills and pals fit your favorite mutation best.
Best Pals in Pew Pew Slime Idle RPG
Whether to boost their own strong points or to cover for their weaknesses, here are the best Legendary and Immortal pals for every mutation branch in Pew Pew Slime Idle RPG.
![]() Frost Seraph | |
![]() Earth Spirit | |
![]() Behemoth Guardian | |
![]() Punk Squad | |
![]() Abyssal Tidelord | |
![]() Nocturnis Dragonlord |
Best Skills in Pew Pew Slime Idle RPG
Because skills in Pew Pew Slime Idle RPG are regarded as a form of equipment, they will also be used to both cover for any weak spots the mutations have, or to polish their strongest suits that can carry you to victory. We've sorted all the Epic, Legendary and Immortal skills which you should seek out for the endgame.
![]() Frost Seraph | |
![]() Earth Spirit | |
![]() Behemoth Guardian | |
![]() Punk Squad | |
![]() Abyssal Tidelord | |
![]() Nocturnis Dragonlord |
Even if you decide you don't like your chosen mutation on your way to its ultimate form, you can reset your slime to its original form and start anew. We hope this tier list will help you make an informed decision from the start, so that you're immediately on the right way! If you liked our Pew Pew Slime Idle RPG guide and enjoy playing idle games, check out Idle Immortal Mythic Clash here on Pro Game Guides.


Abyssal Tidelord







