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Enigma of Sepia Tier List
Image by Pro Game Guides

Enigma Of Sepia Tier List & Reroll Guide – All Characters & Shikigami Ranked (February 2025)

Choose the best units for your formation in Enigma of Sepia!

Enigma of Sepia is a popular idle RPG, featuring tons of popular character anime like Jujutsu Kaisen, Naruto, Dragon Ball, and many more, but with a twist. Every character has been changed into an anime girl. With over 40 characters, finding the best ones can be quite tough. So, to help you with that, here's a complete Enigma of Sepia tier list to help you out.

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All Characters Ranked - Enigma of Sepia Tier List

Enigma of Sepia complete tier list
Image by Pro Game Guides
TierCharacter
SChronis, Elipsea, Erenor, Satorina, Sepia, Yukari, Sanguina, Vespera,
ACelestia, Morgana, Giselle, Crimson, Sandra, Carmilla, Lumina
BBipolaris, Caelestis, Denise, Ginara, Ivy Lynn, Little Rasi, Mentora, Royelle, Nora Zorana, Scientina, Sylphyra
CAqua Sera, Eldwyn, Elysia, Lena Frost, Levia, Little Sai, Nova, Sylvia, Yurina, Naldra
DAlfyria, Aurora, Ayame, Cheshire, Dr. Lorena, Eliza Thorn, Lyra, Mirage

The above tier list gives you an overall view of every character currently available in Enigma of Sepia. The S tier characters are the best characters that you should definitely have on your formation. On the contrary, the D-tier characters are the worst characters that you can have on your team.

In case you haven't got any of the good S or similar characters, you can choose to either invest in your A-tier characters, to awaken them to higher stars. Investing in lower-tier B or C-tier companions is a complete waste of resources, so it's better to avoid them. Rather, you can always try rerolling. In order to ensure you have the best setup in the game, redeem all Enigma of Sepia codes for free rewards.

S Tier Characters - Best Characters in Enigma of Sepia

Elysia in Enigma of Sepia
Screenshot by Pro Game Guides
CharacterRarityPros & Cons
Sanguina in Enigma of Sepia
Sanguina
SP+ Arguably the best P.ATK DPS in the game.
+ Consistently deals True Damage, and targets backlane.
+ Can Slay enemy heroes, if they fall under 10% HP.
Satorina in Enigma of Sepia
Satorina
SP+ Best AoE damage dealer in the game.
+ Can inflict Curse debuffs with a guaranteed chance.
+ Extremely high M.ATK DPS.
Chronis in Enigma of Sepia
Chronis
SP+ Extremely strong self-buffer, with strong buffs.
+ Can inflict Time Stop on enemies, which is one of the best debuffs.
+ Doubles own DPS, Crit Rate, and ATK Spd every time battle starts.
Elipsea in Enigma of Sepia
Elipsea
UR+ One of the best AoE DPS in the game.
+ Strong debuffer with DoT effects like Crow debuff.
+ Great syngery with other top tier characters.
Sepia in Enigma of Sepia
Sepia
UR+ One of the top true damage dealers.
+ Can inflict tons of CC from her skills.
+ Strong syngery skills with other top tier characters.
Vespera in Enigma of Sepia
Vespera
UR+ Best Zenith-type AoE damage dealer.
+ Can purify herself from status effects and CCs.
+ Strong self buff stacking with Transcendence buff.
Yukari in Enigma of Sepia
Yukari
UR+ One of the best tanks in the game.
+ Strong and guaranteed crowd control effects from skills.
+ Can self revive upon receiving lethal blow.
Erenor in Enigma of Sepia
Erenor
UR+ Strong Sword-type tank character.
+ Can deal decent AoE damage, with good debuffs.
+ Removes all buffs from enemies, while granting immunity to self.

A Tier Characters

CharacterRarityPros & Cons
Crimson in Enigma of Sepia
Crimson
SSR+ One of the best magic damage dealers, and has good synergy.
+ Can leech HP, and self heal during battle.
+ Can also inflict debuffs and curses consistently.
Lumina in Enigma of Sepia
Lumina
SSR++ Strong Sword-type AoE damage dealer.
+ One of the best magic-type debuffers.
+ Can trigger chain damage and reduce enemy ATK and DEF.
Morgana in Enigma of Sepia
Morgana
SSR++ One of the best magic supports in game.
+ Can increase SPD, DMG Rate and ATK stats of self as well as allies.
+ Good synergy with other top tier characters.
Carmilla in Enigma of Sepia
Carmilla
SSR++ Fighter and frontline with tons of synergy skills.
+ Can deal significant AoE damage with skills.
+ Has strong defense because of counter capabilities.
Celestia in Enigma of Sepia
Celestia
SSR++ One of the strongest SSR+ heroes, with great DPS.
+ Can self buff with CRIT and CRIT DMG increase significantly.
+ Has good AoE potential, overall balanced kit.
Giselle in Enigma of Sepia
Giselle
SSR++ Versatile frontline with tons of syngery traits.
+ Can trigger Combo skills with guaranteed chance. High DPS output.
+ Becomes extremely overpowered when transforms in Hero Queen state.
Sandra in Enigma of Sepia
Sandra
SSR++ Best healer in the game with good synergy.
+ Can provide AoE healing and splash heals.
+ Can increase Rage points of allies, very strong support.

B Tier Characters

CharacterRarityPros & Cons
Bipolaris in Enigma of Sepia
Bipolaris
SSR+ High synergy, and strong backlane support.
+ Can inflict AoE debuffs like Confusion.
- Lacks overall DPS and low Aptitude.
Caelestis in Enigma of Sepia
Caelestis
SSR+ One of the best tanks in the game.
+ Can provide Barrier to teammates and DMG Res buff on self.
- Dependant on enemy DPS for damage output.
Denise in Enigma of Sepia
Denise
SSR+ Decent tank, with good synergy skills.
+ Strong buffs on self and DPS ally, as well as debuff potential.
- Lacks overall DPS and sustainibility.
Ginara in Enigma of Sepia
Ginara
SSR+ Strong magic damage dealer and backlaner.
+ Good overall DPS with curse and debuff infliction.
- Lacks AoE potential and high skill CD.
Ivy Lynn in Enigma of Sepia
Ivy Lynn
SSR+ Good early game tank, and frontliner.
+ Can shield self as well as allies. Good CC in skillset.
- No DMG reduction, and overall syngery is lacking.
Little Rasi in Enigma of Sepia
Little Rasi
SR+ One of the best SR damage dealers with lots of synergy skills.
+ Has good AoE potential and Rip effects on skills.
- Lacks in stats scaling, especially in late game.
Mentora in Enigma of Sepia
Mentora
SSR+ Decent support and healer, and backlaner.
+ Can provide good healing as well as sheilds to allies.
- Overall survivability is lacking, and no buffing or synergy in skills.
Royelle in Enigma of Sepia
Royelle
SSR+ Strong AoE magic damage dealer.
+ Apart from good DPS, can also inflict curse on enemies.
- Lacks in synergy and stat scaling. Dependant on ally buffs.
Nora Zorana in Enigma of Sepia
Nora Zorana
SSR+ Decently strong AoE frontline. Good synergy.
+ Has good DPS, and inflicts debuffs from skills.
- Requires CC and shields to survive in the late game.
Scientina in Enigma of Sepia
Scientina
SSR+ Arguaby one of the better healers and support.
+ Can deal tons of CC in skillset with decent survivability.
- Lacks buffs or sheilds in skilset.
Sylphyra in Enigma of Sepia
Sylphyra
SSR+ Good DPS and great synergy skills. Best as damage dealer.
+ Can inflict combo attacks as well as self buffs.
- Requires at least 10 stars or above to be useful in late game.

C Tier Characters

CharacterRarityPros & Cons
Aqua Sera in Enigma of Sepia
Aqua Sera
SR+ Decently strong AoE P.ATK damage dealer.
+ Can provide self buffs and good synergy skills.
- Bad stats scaling before 10 stars.
Eldwyn in Enigma of Sepia
Eldwyn
SR+ High synergy, decent DPS frontline character.
+ Can inflict bleed debuff on enemies.
- Self damage via sacrifice is too high. Dies quickly.
Elysia in Enigma of Sepia
Elysia
R+ Arguably the best R-rarity damage dealer.
+ Decent synergy skills, AoE potential and debuffs from skills.
- Requires tons of investment and star-ups to be useful. Not viable in late game.
Lena Frost in Enigma of Sepia
Lena Frost
SR+ Good DPS and line-based damage output.
+ Can also inflict debuffs from skills. Great at early game.
- Lacks almost any synergy and aptitude.
Levia in Enigma of Sepia
Levia
SR+ Similar to Lena Frost in every way.
+ Cannot inflict line damage, rather assists ally attacks.
- Lacks good synergy skills and aptitude.
Little Sai in Enigma of Sepia
Little Sai
SR+ Decent AoE P.ATK damage dealer.
+ Can act as good frontline, tons of synergy skills.
- Scaling is lackluster, overall outclassed by better options.
Naldra in Enigma of Sepia
Naldra
SSR+ Can inflict Curse and Burn debuffs from attacks.
+ Decent magic damage backliner and debuff support.
- Weakest SSR, lacks overall usability or synergy skils.
Nova in Enigma of Sepia
Nova
SR+ Good frontline tank and fighter.
+ Can reflect damage decently, and provide shields.
- Good at early game, but lacks in late game. Dies quickly.
Sylvia in Enigma of Sepia
Sylvia
SR+ Strong damage dealer with decent Slay effects on attack.
+ Can inflict Bleed debuffs from attack.
- Lacks in overall DPS and skill damage. Depends on buffs.
Yurina in Enigma of Sepia
Yurina
SR+ Decent early-mid game tank with Taunt skill.
+ Can provide DMG RES buffs, and good synergy.
- Lacks crowd control, and lackluster buffs. Better options available.

D Tier Characters

CharacterRarityPros & Cons
Alfyria in Enigma of Sepia
Alfyria
R+ Decent early game tank. Can self heal and shield.
- Lacks in stats scaling in later stages.
- Bad overall synergy and usability.
Aurora in Enigma of Sepia
Aurora
R+ Can provide decent buffs and inflict debuffs.
- Overall DPS is very low.
- Much better M.ATK options available.
Ayame in Enigma of Sepia
Ayame
R+ Can inflict AoE damage and self buff.
- Lackluster DPS and overall damage output.
- No good synergy, or late game viability.
Cheshire in Enigma of Sepia
Cheshire
R+ Can inflict burst damage and provide debuffs.
- Damage amount is low, even with investment.
- Debuffs don't last, and are very minor in effect.
Dr Lorena in Enigma of Sepia
Dr. Lorena
R+ Decent R-rarity healer with good synergy.
- Healing provided is very low.
- Doesn't perform well in PvP or PvE stages.
Eliza Thorn in Enigma of Sepia
Eliza Thorn
R+ Decent M.ATK AoE damage dealer.
- Inflicts Curse that also effects self.
- Doesn't scale well in mid-late game.
Lyra in Enigma of Sepia
Lyra
R+ Subpar tank with counter abilities.
- Bad synergy and low defensive stats.
- Skills lack almost any CC or defense.
Mirage in Enigma of Sepia
Mirage
R+ Subpar AoE P.ATK damage dealer.
- Outclassed by almost every other P.ATK character.
- Skills lacks DPS and viability in most game modes.

All Shikigami Ranked - Enigma of Sepia Tier List

Shikigami Tier List in Enigma of Sepia
Image by Pro Game Guides

Apart from your characters, one more essential part of your formation is your Shikigami choices. These are celestial beings whom you can summon during the fight, and they can essentially turn the tide of the battle. But with multiple options available, here's a tier list to help you choose the best ones:

ShikigamiTierPros & Cons
Tsukuyomi in Enigma of Sepia
Tsukuyomi
(UR)
S+ Extremely high AoE burst damage on summon.
+ Can inflict Slow as well as Eclipse that reflects 150% of the enemy's damage.
+ Significantly buffs allies M.DMG and shields the frontline every turn.
Ibaraki in Enigma of Sepia
Ibaraki
(SSR+)
A+ Great AoE damage on Rage skill.
+ Can significantly reduce enemy DEF and ATK with debuffs.
+ Provides decent support and scaling.
Aoandon in Enigma of Sepia
Aoandon
(SSR+)
A+ Good Burst damage potential with a chance to cause AoE damage.
+ Inflicts Infernal Flame debuff, which increases every debuff stack as well as causes HP% DoT.
+ Increases P.DMG significantly and boosts allies' Rage Skill Strength every turn.
Ootengu in Enigma of Sepia
Ootengu
(SSR+)
B+ Deals decent AoE damage upon using Rage skill.
+ Can inflict Slow and ATK Down debuffs if skills hit.
- Overall scaling isn't high and lacks support.
Otakemaru in Enigma of Sepia
Otakemaru
(SSR+)
B+ Provides decent AoE damage through Rage skill.
+ Can shield and boost M.DMG of allies every turn.
- Can inflict CC, but only has a 35% chance to hit. Lacks scaling.
Onimusha in Enigma of Sepia
Onimusha
(SSR)
C+ Can inflict decent Burst damage as well as some True DMG.
- Lacks AoE potential as well as scaling.
- Passive skill buffs aren't strong, and not guaranteed (15% to trigger).

How to reroll in Enigma of Sepia?

SSR ranked summoning in Enigma of Sepia
Screenshot by Pro Game Guides

In case you're unhappy with your character pulls in Enigma of Sepia, you can choose to reroll your account in hopes of getting SSR+ or even UR rarity heroes from the summon. So, here's a step-by-step guide on how to do that:

  1. Log in to Enigma of Sepia as a Guest. Complete the five minute tutorial.
  2. Perform 10-summon and see if you got your desired character.
  3. If not, head to 'Profile' screen on top right. Then select 'Switch Account',
  4. Once at login, select a new server or select 'Login as Guest' to old server.
  5. Create the new account, and complete the tutorial again to reroll.

Enigma of Sepia Summon Drop Rates

To help you get a better idea of the summon probabilities in Enigma of Sepia, here's a detailed breakdown of what you can summon.

  • SSR+ rarity summon drop chance: 0.93%
  • SSR rarity summon drop chance: 0.93%
  • SR rarity summon drop chance: 0.69%
  • R rarity summon drop chance: 1.36%

The overall drop chance to get a character from an Elite Summon is capped at 10%, whereas the chance to get character token is 40% followed by the remaining 50% for in-game items.

For more on Tier Lists, check out Wacky Squad Tier List – All Characters Ranked or Etheria Restart Tier List & Reroll Guide on Pro Game Guides!


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Author
Image of Sudhanyo Chatterjee
Sudhanyo Chatterjee
Sudhanyo Chatterjee has nearly six years of writing experience, with four focused on the gaming industry. He specializes in RPGs, strategy games, and mobile game guides. His favorite titles include the Diablo series and strategy staples like Total War and Age of Empires.