Rockstar kept the same voice actors from the original game while remixing some audio. The game shows its age during some sections, but it makes the game feel that much more like its PlayStation 2 counterpart.
Related: All Characters and Voice Actors in Sherlock Holmes Chapter One
| Voice Actor | Character |
| Al Espinoza | Miguel |
| Chris Phillips | El Burro/Marty Chonks |
| Cynthia Farrell | Catalina |
| Deborah "Debi" Mazar | Maria Latore |
| Frank Chavez | Fernando Martinez |
| Frank Vincent Gattuso | Salvatore Leone |
| Hunter Platin | Phil Cassidy/Curly Bob/Chico |
| Joseph Peter "Joe" Pantoliano | Luigi Goterelli |
| Kim Gurney | Misty |
| Kyle MacLachlan | Donald Love |
| Les J.N. Mau | Kenji Kasen |
| Lianna Pai | Asuka Kasen |
| Michael Madsen | Toni Cipriani |
| Michael Rapaport | Joey Leone |
| Renaud Sebbane | Carlos |
| Robert Loggia | Ray Machowski |
| Sondra James | Ma Cipriani |
| The Guru/Keith Elam | 8-Ball |
| Walter Mudu | King Courtney/D-Ice |
The talent picked for the game set a growing standard for Rockstar's titles. The supporting cast was even made up of real DJs and radio announcers to keep the feeling of authenticity. The main cast has so much talent with some impressive acting history.
Debi Mazar has acted in Goodfellas and Collateral, with Michael Madsen acting in Reservoir Dogs and other Tarantino movies such as The Hateful Eight. Frank Vincent's background working in The Sopranos and Goodfellas alongside Joe Pantoliano's own acting history in Daredevil and The Matrix fills the game with stars from all over.
For more lists of voice actors, check out All Characters and Voice Actors in Call of Duty: Vanguard on Pro Game Guides.
Adam Aguilar has been playing a variety of genres since childhood but gravitates towards story driven RPGs like the Final Fantasy series or horror games like the Resident Evil and Silent Hill series. He enjoys analyzing themes found within video games and has been writing about them for over 5 years now. As a Contributing Writer for PGG, Adam has been known to cover anything from Phasmophobia to Genshin Impact!