Resident Evil 4 Remake – Best Weapon Tier List

A horde of weapons is hidden throughout Resident Evil 4 Remake, from handguns and shotguns to knives and rocket launchers. But which ones are the cream of the crop, the pièce de résistance? Here's the Resident Evil 4 Remake best weapon tier list so you know which you should get your hands on.

Best RE4 Weapons, Ranked

You'll come across seven weapon types across Leon's adventure through rural Spain: handguns, magnums, rifles, submachine guns, shotguns, knives, and special weapons. The following list is sorted from best to worst so you can easily find the most useful weapons in RE4 Remake weapon, based on ammo capacity, effectiveness, and strength.

Related: Are the Sentinel Nine & Skull Shaker worth buying in Resident Evil 4 Remake?

Best RE4 Remake handgun

The Red9 is the best handgun in the RE4 Remake. Why? Because it's so powerful, it can take out most mob enemies with a single, well-placed headshot when others can take two or three. Once you get the stock, you become a force to be reckoned with.

Best RE4 Remake magnum

The Killer7 is the best magnum in Resident Evil Remake. It comes equipped with a laser sight for ultimate accuracy, meaning you can pop heads with ease. It also has higher base stats than other magnums in the Resident Evil 4 Remake, making it the best choice.

Best RE4 Remake rifle

The Stingray is the best rifle in RE4 Remake. It has a 3x damage multiplier against enemy weak spots and is the best weapon to use at medium to long range. It's also compatible with multiple scopes.

Best RE4 Remake submachine gun

The LE 5 is the best SMG in Resident Evil Remake. It has an incredibly high fire rate and damage output, making it the perfect choice against enemy waves. It's also compatible with scopes, meaning you can shred from a distance.

Best RE4 Remake shotgun

Arguably the best weapon type in the game, the Shotgun's best pick is the Striker. Pair its wide-spread shot with the fact it's a semi-auto, and you've got a clear winner against mobs. It also has the 2x Ammo Capacity Perk when upgraded, making it a certified banger, literally.

Best RE4 Remake knife

If knives are your thing, the Fighting Knife is the best pick purely based on its damage output. It has decent durability at 1.40 but expect to be repairing it just as often as the other knives.

For more information on Resident Evil 4 Remake, check out All Castle Gate Blue Medallion locations in Resident Evil 4 Remake on Pro Game Guides.