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Resident Evil 4 Remake – How to kill Regenerators

Seek and destroy.

There are many sinister enemies in Resident Evil 4 Remake, and some are hard to beat. One of those monsters is Regenerators. These enemies can regenerate their limbs and even their heads. That's because the real enemy is a parasite inside the body that needs to be killed. Here's how to defeat Regenerators in Resident Evil 4 Remake.

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How to beat Regenerators in Resident Evil 4 Remake

To kill Regenerators in Resident Evil 4 Remake, locate a parasite, Plaga, on the monster's body and shoot or destroy him with explosives. There are several ways you can do this:

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  • Use the thermal scope to find parasites - You can locate them in the body via thermal vision, making it easier to kill them. There are usually several parasites in the body. There's even an achievement for getting three of them with a single bullet!
  • Use high-damage weapons - Don't waste your precious ammo against Regenerators, as they can receive significant damage with ease. Instead, use a shotgun or rocket launcher to blast them quickly.
  • Use explosives - Explosives and grenades are the most effective option against Regenerators.
  • Use a knife(if necessary) - while a knife can be effective, you might want to think of other options. As durability is implemented in Resident Evil 4 Remake, you may break your weapon. Hence, use it only if you have no other option.

Best tips for beating Regenerators in Resident Evil 4 Remake

Regenerators in Resident Evil 4 Remake are even more challenging than in the original, as you can use a knife just to stab them from the back. The blade will break, so try to be more tactical.

  • Don't waste ammo, as Regenerators are real sponges when it comes to taking damage.
  • Avoid cutting off the legs of Regenerators, as it will make them harder to hit while they crawl.
  • Instead of shooting them, try to blast Regenerators with explosives. It's faster and more fun!

For more information on Resident Evil 4 Remake, check out Best RE4 Remake mods here on Pro Game Guides!


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Image of Nebojša Prijić
Nebojša Prijić
Nebojša Prijić is a Managing Editor at Pro Game Guides with over 25 years of experience in journalism, screenwriting, and copywriting. He previously worked as Editor-in-Chief of Maxim Serbia magazine and the IGN Adria website. Nebojša is an old-school gamer who loves real-time strategies, shooters, and RPGs, but most of all, he plays Roblox and mobile games with his son. He remembers the first Diablo, PC games on a single floppy disk, and playing Mortal Kombat on the keyboard.