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Mewtwo in Pokemon Go.

Best Mewtwo Moveset in Pokémon Go

Mewtwo will surprise you too when it turns opponents to goo. Who knew? Best moves below!

We here at Pro Game Guides feel like Mewtwo gets a bad rap. It was #150 in the original Gen 1 Pokémon list and has frequently been used as a sort-of-villain-but-sort-of-victim throughout the entire franchise. Still, regardless of where it came from, who its mother is, and what its intentions are — Mewtwo is an immensely strong Pokémon, and it doesn't look like that will ever change. In this guide, we're going over its best moves and basic stats.

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Best Mewtwo Moveset in Pokémon Go

The best movesets for Mewtwo sometimes depend on the technique you use as a player and the Pokémon the opponent is using. However, in this guide, we will cover the top-ranking movesets based on their average stats for damage and success.

Before we list the movesets, we're going to cover a few basic stats about Mewtwo, so you can adequately prepare your playstyle and pick the appropriate movesets.

Basic Stats

  • Type(s): Psychic
  • Heavy Weakness(es): None
  • Weakness(es): Bug, Dark, Ghost
  • Resistance(s): Fighting, Psychic
  • Strong Resistance(s): Poison, Psychic
  • Boosted By: Windy Weather
  • Max CP: 4724
  • Attack | Defense | Stamina: 300 | 182 | 214

Related: Best Metagross Moveset in Pokémon Go - Pro Game Guides

Best Movesets

The following two moves reflect the attacks that show up the most frequently on the top 10 movesets. While this generally means this is the best move of that type, it's not guaranteed.

  • #1 Fast Attack: Psycho Cut
  • #1 Charge Attack: Psystrike

The remaining movesets are the top 10 movesets for Mewtwo, ranked by DPS (damage per second).

  • #1
    • DPS: 22.39
    • Fast Attack: Psycho Cut
    • Charge Attack: Psystrike
  • #2
    • DPS: 21.51
    • Fast Attack: Confusion
    • Charge Attack: Psystrike
  • #3
    • DPS: 21.13
    • Fast Attack: Confusion
    • Charge Attack: Psychic
  • #4
    • DPS: 20.98
    • Fast Attack: Psycho Cut
    • Charge Attack: Psychic
  • #5
    • DPS: 19.87
    • Fast Attack: Confusion
    • Charge Attack: Flamethrower
  • #6
    • DPS: 19.82
    • Fast Attack: Psycho Cut
    • Charge Attack: Flamethrower
  • #7
    • DPS: 18.97
    • Fast Attack: Confusion
    • Charge Attack: Shadow Ball
  • #8
    • DPS: 18.22
    • Fast Attack: Confusion
    • Charge Attack: Ice Beam
  • #9
    • DPS: 18.20
    • Fast Attack: Psycho Cut
    • Charge Attack: Thunderbolt
  • #10
    • DPS: 18.09
    • Fast Attack: Psycho Cut
    • Charge Attack: Shadow Ball

Attack Types

Similar to Pokémon, attacks have a type (i.e., Fighting, Fairy, Psychic, etc.). In the list below, we list the attack type of every attack mentioned in the movesets for Mewtwo above. Use this list to determine the best moves against the Pokémon your Mewtwo is fighting.

  • Fire-type Attacks
    • Mewtwo's Moves
      • Flamethrower
    • Super Effective Against: Bug, Grass, Ice, Steel
    • Not Very Effective Against: Dragon, Fire, Rock, Water
  • Ice-type Attacks
    • Mewtwo's Moves
      • Ice Beam
    • Super Effective Against: Dragon, Flying, Grass, Ground
    • Not Very Effective Against: Fire, Ice, Steel, Water
  • Electric-type Attacks
    • Mewtwo's Moves
      • Thunderbolt
    • Super Effective Against: Flying, Water
    • Not Very Effective Against: Dragon, Electric, Grass, Ground
  • Dark-type Attacks
    • Mewtwo's Moves
      • Shadow Ball
    • Super Effective Against: Ghost, Psychic
    • Not Very Effective Against: Dark, Normal
  • Psychic-type Attacks
    • Mewtwo's Moves
      • Psycho Cut
      • Psystrike
      • Confusion
    • Super Effective Against: Fighting, Poison
    • Not Very Effective Against: Dark, Psychic, Steel

With these lists, you'll know when to use Mewtwo and how to use him most effectively. Good luck battling!

Want to know the strongest moveset for other Pokemon? Check out our guides for Charizard and Dialga!


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Nicholas Fries
Freelance writer and jack-of-all-hobbyist-tech-development-trades (website, game, and program). My passion is to create content that entertains and makes people think critically.